| Advantage of Superbiochips' tissue array |
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1. Uniform procedure |
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Using tissue array technology, each tissue sample is treated in
an identical manner. Like conventional formalin-fixed paraffin embedded
material, tissue microarrays are amenable to a wide range of techniques
including histochemical stains, immunologic stains with either chromogenic
or fluorescent visualization, in situ hybridization (including both
mRNA ISH and FISH), and even tissue micro-dissection techniques.
For each of these protocols, conventional sections can have substantial
slide to slide variability associated with processing 300 slides
(for example, 20 batches of 15 slides). The tissue microarrays allow
the entire cohort to be analyzed in one batch on a single slide.
Thus reagent concentrations are identical for each case, as are
incubation times and temperatures, wash conditions, and antigen
retrieval, if necessary.
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2. Saving the assay volume |
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Only a very small amount of reagent is required to analyze an entire
cohort using tissue array. This advantage raises the possibility
of use of tissue microarrays in screening procedures (for example
in hybridoma screening), a protocol that is impossible using conventional
sections. It also saves money when reagents are costly.
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3. Large cores |
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Unlike other Companies' tissue array which is 1.0 mm or 0.6 mm
diameter, Superbiochips supply the large core samples which is 2.0
mm in diameter. Larger cores provide the enough area to be interpreted,
and analysis time for the researchers is markedly reduced.

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4. Fresh slide |
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Unlike other companies, which perform serial sectioning all the
array block at a time and stock the slides, Superbiochips always
are shipping the fresh slides. Furthermore, slides are maintained
in an anoxic state by special treatment with inert gas packing.
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5. No adhesive tape for sectioning |
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In most of the laboratories, adhesive coated tape is used for sectioning
the tissue array. Unfortunately, trace amount of adhesive material
remains in the slides and interferes the subsequent immunohistochemistry
reaction. Our tissue array are sectioned by expert laboratory technicians,
and serial sectioning procedure can be succesfully performed without
aid of adhesive tape.
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6. Long shelf life |
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While the production of large batches of microarray sections is
most efficient, it raises a problem of antigenic loss during the
storage. Some reports proved the loss of antigenicity if sections
are stored for as little as two weeks prior to immunostaining. Superbiochips
overcome this antigenic loss by special package to maintain anoxic
state. Storing in a refrigerator is recommended for delaying the
antigenic loss.
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