About tissue array  
What is tissue array
Advantages
FAQ
Gallery

Advantage of Superbiochips' tissue array

1. Uniform procedure
2. Saving the assay volume
3. Large cores
4. Fresh slide
5. No adhesive tape for sectioning
6. Long shelf life

1. Uniform procedure

Using tissue array technology, each tissue sample is treated in an identical manner. Like conventional formalin-fixed paraffin embedded material, tissue microarrays are amenable to a wide range of techniques including histochemical stains, immunologic stains with either chromogenic or fluorescent visualization, in situ hybridization (including both mRNA ISH and FISH), and even tissue micro-dissection techniques. For each of these protocols, conventional sections can have substantial slide to slide variability associated with processing 300 slides (for example, 20 batches of 15 slides). The tissue microarrays allow the entire cohort to be analyzed in one batch on a single slide. Thus reagent concentrations are identical for each case, as are incubation times and temperatures, wash conditions, and antigen retrieval, if necessary.

2. Saving the assay volume

Only a very small amount of reagent is required to analyze an entire cohort using tissue array. This advantage raises the possibility of use of tissue microarrays in screening procedures (for example in hybridoma screening), a protocol that is impossible using conventional sections. It also saves money when reagents are costly.

3. Large cores

Unlike other Companies' tissue array which is 1.0 mm or 0.6 mm diameter, Superbiochips supply the large core samples which is 2.0 mm in diameter. Larger cores provide the enough area to be interpreted, and analysis time for the researchers is markedly reduced.

4. Fresh slide

Unlike other companies, which perform serial sectioning all the array block at a time and stock the slides, Superbiochips always are shipping the fresh slides. Furthermore, slides are maintained in an anoxic state by special treatment with inert gas packing.

5. No adhesive tape for sectioning

In most of the laboratories, adhesive coated tape is used for sectioning the tissue array. Unfortunately, trace amount of adhesive material remains in the slides and interferes the subsequent immunohistochemistry reaction. Our tissue array are sectioned by expert laboratory technicians, and serial sectioning procedure can be succesfully performed without aid of adhesive tape.

6. Long shelf life

While the production of large batches of microarray sections is most efficient, it raises a problem of antigenic loss during the storage. Some reports proved the loss of antigenicity if sections are stored for as little as two weeks prior to immunostaining. Superbiochips overcome this antigenic loss by special package to maintain anoxic state. Storing in a refrigerator is recommended for delaying the antigenic loss.

@2004~2005.SuperBioChips Laboratories, All rights reserved. 118-88 Yongdu-dong, Seoul 130-820, KOREA.
Tel +82-2-3676-8270, Fax +82-2-3676-8269